1. Report Overview
1.1 Cell-Based Assays Overview
1.2 Cell-Based Assays Market Segmentation
1.3 Why You Should Read This Report
1.4 How This Report Delivers
1.5 Questions Answered by this Report
1.6 Who is this Report for?
1.7 Research Methods and Analysis
1.8 Frequently Asked Questions
1.9 Associated Reports
1.10 About Visiongain
2. Introduction to Cell-Based Assays and Applications
2.1 Cost of New Drug Discovery and Development Reaches $2.6bn – Companies Constantly Looking for Increased Efficiencies
2.2 Drug Discovery Approaches – Target-Based and Phenotype-Based Discovery
2.3 Drug Screening Assays
2.4 Animal Models Present In Vivo Conditions: But Do Results Translate to Humans?
2.5 Biochemical Assays and their Advantages over Animal Models
2.5.1 Applications of Biochemical Assays
2.5.2 Lead Identification and Toxicity Testing
2.6 Cell-Based Assays and their Advantages
2.7 2D vs 3D Cell-Based Assays
2.8 Advanced Cell-Based Assays
2.9 The Different Assay Detection Methods and Technologies
2.10 Cells used in Cell-Based Assays
2.10.1 Immortalised Cell Lines – Convenient but not Truly Representative of Normal Human Cell Lines
2.10.2 Primary Cells: Closer to the In Vivo Environment
2.10.3 Stem Cells: Potential to Overcome Limitations of Primary cells and Immortalised Cell Lines
2.11 Uses for Cell-Based Assays in Drug Discovery and Development
2.11.1 Target Validation
2.11.2 Primary Screening
2.11.3 Secondary Screening
2.11.4 ADME Screening
2.11.5 High Throughput Screening: Greatly Increases Efficiency
3. World Cell-Based Assays Market 2016-2026
3.1 Global Cell-Based Assays Market Forecast 2016-2026
3.2 Drivers for the Cell-Based Assays Market
3.3 Restraints for the Cell-Based Assays Market
3.4 Cell-Based Assays: Market Segments – Products and Services
3.5 Cell-Based Assays, Market Segments: Products Forecast 2016-2026
3.5.1 The Four Main Categories of Cell-Based Assay Products
3.5.1.1 Equipment Needed to Conduct Cell-Based Assays
3.5.1.2 Disposables Necessary to Perform Cell-Based Assays
3.5.1.3 Consumables Forming the Basis of Cell-Based Assays
3.5.1.4 Biobanks
3.6 Cell-Based Assays Market Segments: Services
3.6.1 Cell-Based Assays Market Segments: Services Forecast 2016-2026
3.7 Cell-Based Assays Market: Applications Forecasts 2016-2026
3.7.1 Drug Discovery Segment
3.7.2 ADME (Absorption, Distribution, Metabolism, Excretion) Segment
3.7.3 Basic Research Segment
4. Leading National Markets for Cell-Based Assays, 2016-2026
4.1 Regional Breakdown of the Global Cell-Based Assays Market, 2016-2026
4.2 Global Cell-Based Assays market: Regional Forecast 2016-2026
4.3 The US Cell-Based Assays Revenue Forecast 2016-2026
4.4 European Union (EU) Cell-Based Assays Market 2016-2026
4.4.1 IMI’s Pan-European Drug Discovery Platform holds Much Promise
4.4.2 EU National Market Share Breakdown, 2015, 2020 and 2026
4.4.3 EU Market: Main National Forecasts, 2016-2026
4.4.4 German Cell-Based Assay Revenue Forecast, 2016-2026
4.4.5 French Cell-Based Assays Revenue Forecast, 2016-2026
4.4.6 UK Cell-Based Assays Revenue Forecast, 2016-2026
4.4.7 Spanish Cell-Based Assays Revenue Forecast, 2016-2026
4.4.8 Italian Cell-Based Assays Revenue Forecast, 2016-2026
4.5 Japanese Cell-Based Assays Revenue Forecast, 2016-2026
4.6 BRIC Nations (Brazil, Russia, India and China) Cell-Based Assays Market
4.6.1 BRIC Countries National Breakdown, 2015, 2020 and 2026
4.6.2 BRIC Countries National Forecasts, 2016-2026
4.6.3 Chinese Cell-Based assay Revenue Forecast, 2016-2026
4.6.4 Indian Cell-Based Assays Revenue Forecast, 2016-2026
4.6.5 Russian Cell-Based Assays Revenue Forecast, 2016-2026
4.6.6 Brazilian Cell-Based Assays Revenue Forecast, 2016-2026
5. Leading Companies in the Cell-Based Assays Market: Product Suppliers, 2016
5.1 Thermo Fisher Scientific
5.1.1 ThermoFisher Scientific Financial Figures
5.1.2 Recent Developments at ThermoFisher Scientific
5.1.2.1 ThermoFisher Acquires Affymetrix
5.1.3 Cell-Based Assay Technologies under ThermoFisher’s Life Science Solutions Segment
5.2 DiscoveRx
5.2.1 DiscoveRx Assay Platforms and Technology
5.3 PerkinElmer
5.3.1 AlphaScreen Technology
5.3.2 DELFIA TRF Assays
5.3.3 Label-Free Cellular Assay Detection/Opera System
5.4 BD (Becton, Dickinson and Company)
5.4.1 Cell-Based Assays Through BD Life Sciences
5.5 InSphero
5.5.1 GravityPLUS – Leading Solution for 3D Cell-Based Assays
5.6 QGel
5.6.1 QGel Products and Services
5.7 Biocroi
5.7.1 Happy Cell ASM and its 3D Cell Culture
5.8 GE Healthcare
5.8.1 Cell-Based Assays Through GE Healthcare Life Sciences
5.9 Molecular Devices
5.9.1 Cell-Based Assay Products Include SpectraMax Microplate Readers and FLIPR Tetra System
5.10 Promega
5.10.1 Assays Range from Cell Viability Assays to Mitochondrial Function Assays
5.11 BioVision
5.11.1 Cell-Based Assays Include the EZCell Platform and a Cholesterol Detection Kit
6. Leading Companies in the Cell-Based Assays Market: CROs and Service Providers, 2016
6.1 Porsolt: Acquires Fluofarma
6.1.1 Fluofarma
6.1.2 Fluofarma has Over 100 Cell-Based Assays
6.2 CYTOO
6.2.1 Cell Micropatterning to Eliminate Trade-off Between Quantity and Quality?
6.2.2 Cell-Based Assays for Muscular Atrophy/Hypertrophy and Anti-Cancer Drug Profiling
6.3 Cell Assay Innovations (CAI)
6.3.1 ClariCELL Technology
6.4 ProQinase
6.4.1 ProQinase Cell-Based Assay Services, 2016
6.5 Charles River Laboratories
6.5.1 PhenoFocus – Portfolio of over 100 Primary Cell-Based Assays
6.6 BioAgilytix
6.7 SGS
6.7.1 Offers a Range of Services, Including 3D Cell-Based Assays
6.8 Pharmaceutical Product Development
6.9 Marin Biologic Laboratories
7. Cell-Based Assays Technology, Trends and Future Outlook
7.1 Stem Cells: Vast Potential
7.1.1 The Benefits of Using Stem Cells in Cell-Based Assays
7.1.2 iPSCs: An Uncontroversial and Abundant Source
7.1.3 Companies Providing Stem Cell-Based Assays
7.2 Toxicity Testing: Important Field for Cell-Based Assays
7.3 3D Systems: The Advantages of Next Generation of Cell Systems
7.3.1 Complexity of 3D Systems is a Challenge but More are Reaching the Market
7.3.2 Organoids – The Future of Drug Development?
7.3.2.1 Hurdles to the Future Organoid Market
7.3.2.2 Organoids Now and in the Future
7.3.3 Bio-Printing for Drug Development: Using 3D Printing Technology
7.4 Increasing Outsourcing of Cell-Based Assays
7.5 Label-Free Technology
7.6 GPCRs: A Common Drug and Drug Discovery Target
7.6.1 GPCRs in Cell-Based Assays
7.6.2 Allosteric GPCRs
7.7 Increasing Miniaturisation and Automation
7.7.1 Advantages of Miniaturisation
7.7.2 Advantages of Automation
7.8 Microfluids are Set to be a Trend
7.8.1 The Potential Challenges to Microfluids
7.9 Multiplexing: Improves Efficiency of cell-Based Assays
7.9.1 Advantages will Drive Growth
7.10 High Content Screening: A Well Established Tool
7.10.1 The Future for HCS: Will Continue to Expand, Still Room for Innovation
7.11 Cell-Based Assays for the Development of Biologics
8. Qualitative Analysis of the Cell-Based Assays Market, 2016
8.1 SWOT Analysis of the Cell-Based Assays Market
8.1.1 Strengths Within the Cell-Based Assay Market
8.1.2 Weaknesses Within the Cell-Based Assays Market
8.1.3 Opportunities for the Cell-Based Assays Market
8.1.4 Threats to the Cell-Based Assays Market
8.2 STEP Analysis of the Cell-Based Assays Market
8.2.1 Social Factors
8.2.2 Technological Factors
8.2.3 Economic Factors
8.2.4 Political Factors
9. Research Interviews
9.1 Interview with Dr Colin Sanctuary, CEO of QGel
9.1.1 On the Definition of Cell-Based Assays
9.1.2 On QGel Company Background and QGel Offerings
9.1.3 On the Cell-Based Assay Market Now and in the Future
9.1.4 On the Challenges to Cell-Based Assays and the Cell-Based Assay Market
9.1.5 On Considerations to Take when Purchasing Cell-Based Assays
10. Conclusions from the Research and Analysis
10.1 Growth Has Been Driven by Advantages of Cell-Based Assays
10.2 Current Status of the Market and its Growth Drivers
10.3 The Most Dominant National Markets and Emerging Countries
10.4 Future Trends and Technology
Table 2.1 Main Parameters Required in Drug Discovery and Development
Table 2.2 Selected Label-Free Detection Technologies Used for Cell-Based Assays, 2016
Table 2.3 Cell-Based Assays for HTS in Drug Screening, 2016
Table 3.1 Global Cell-Based Assays Market Forecast: Revenues ($m), AGR (%) and CAGR (%), 2016-2026
Table 3.2 Global Cell-Based Assays Market Forecast: Revenues ($m), AGR (%) and CAGR (%), 2016-2026
Table 3.3 Cell-Based Assays Market Segments: Products Forecast - Revenue ($m), AGR (%), CAGR (%), Market Share (%), 2016-2026
Table 3.4 Cell-Based Assays Market Segments: Services Forecast- Revenue ($m), Market Share (%), AGR (%), CAGR (%), 2016-2026
Table 3.5 Cell-Based Assays Market Application Forecasts: Revenue ($m), Market Share (%), AGR (%), CAGR (%), 2016-2026
Table 3.6 Drug Discovery Segment Forecast: Revenue ($m), AGR (%), CAGR (%), Market Share (%), 2016-2026
Table 3.7 ADME Segment Forecast: Revenue ($m), Market Share (%), AGR (%), CAGR (%), 2016-2026
Table 3.8 Basic Research Segment Forecast: Revenue ($m), Market Share (%), AGR (%), CAGR (%), 2016-2026
Table 4.1 Cell-Based Assays Market Breakdown by Region: Revenues ($m), Market Shares (%), 2015
Table 4.2 Cell-Based Assays Market Breakdown by Region: Revenues ($m), Market Shares (%), 2020
Table 4.3 Cell-Based Assays Market Breakdown by Region: Revenues ($m), Market Shares (%), 2026
Table 4.4 Global Cell-Based Assays Market Regional Forecasts: Revenues ($m), AGR (%), CAGR (%), Market Shares (%), 2016-2026
Table 4.5 US Cell-Based Assays Market Forecast: Revenues ($m), AGR (%),Market Shares (%), CAGR (%), 2016-2026
Table 4.6 EU Cell-Based Assays Market Forecast: Revenues ($m), AGR (%), World Market Shares (%), CAGR (%), 2016-2026
Table 4.7 EU Market Breakdown by Leading Nation: EU Market Shares (%), Global Market Shares (%) and Revenues ($m), 2015
Table 4.8 EU Market Breakdown by Leading Nation: EU Market Shares (%), Global Market Shares (%) and Revenues ($m), 2020
Table 4.9 EU Market Breakdown by Leading Nation: EU Market Shares (%), Global Market Shares (%) and Revenues ($m), 2026
Table 4.10 EU Market, Leading Five National Forecasts: Revenue ($m), AGR (%),Market Share (%), CAGR (%), 2016-2026
Table 4.11 German Cell-Based Assays Market Forecast: Revenues ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.12 French Cell-Based Assays Market Forecast: Revenues ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.13 UK Cell-Based Assays Market Forecast: Revenues ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.14 Spanish Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Table 4.15 Italian Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Table 4.16 Japanese Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Table 4.17 BRIC Countries Breakdown by Nation: BRIC market Shares (%), Global Market Shares (%) and Revenues ($m), 2015
Table 4.18 BRIC Countries Breakdown by Nation: EU market Shares (%), Global Market Shares (%) and Revenues ($m), 2020
Table 4.19 BRIC Countries Breakdown by Nation: EU market Shares (%), Global Market Shares (%) and Revenues ($m), 2026
Table 4.20 BRIC National Forecasts: Revenue ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.21 Chinese National Forecasts: Revenue ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.22 Indian National Forecasts: Revenue ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.23 Russian National Forecasts: Revenue ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 4.24 Brazilian National Forecasts: Revenue ($m), AGR (%), Market Share (%), CAGR (%), 2016-2026
Table 5.1 ThermoFisher Scientific Historical Sales: Revenue ($m), AGR (%), 2010-2015
Table 5.2 Life Technologies Cell-Based Assay Technology Overview, 2016
Table 5.3 Life Technologies Cell-Based Assay Technology Overview, 2016
Table 5.4 Other DiscoveRx Assay Platforms, 2016
Table 5.5 PerkinElmer Revenue Breakdown: Revenue ($m) for Fiscal Year Ending 3rd January 2016
Table 5.6 QGel Products and Services Cell-Based Assay Products, 2016
Table 5.7 GE Healthcare Life Sciences Cell-Based Assay Products, 2016
Table 6.1 ProQinase Cell-Based Assay Services, 2016
Table 6.2 Charles River Laboratories Revenue Breakdown: Revenue ($m), 2013-2015
Table 6.3 Cell-Based Assay Platforms, Details and Benefits Used by BioAgilytix , 2016
Table 7.1 Selected Companies with Involvement in Stem Cell-Based Assays, 2016
Table 7.2 Selected Companies Offering Label-Free Assay Systems, 2016
Figure 1.1 Cell-Based Assays Market Segmented by Application
Figure 1.2 Cell-Based Assays Market Segmented by Sector
Figure 1.3 Cell-Based Assays Products Market Segments
Figure 2.1 Stages of Pre-Clinical Drug Development
Figure 3.1 Global Cell-Based Assays Market Forecast: Revenue ($m), 2016-2026
Figure 3.2 Drivers and Restraints for the Cell-Based Assays Market, 2016
Figure 3.3 Cell-Based Assays Market Segments Forecasts: Revenue ($m), 2016-2026
Figure 3.4 Cell-Based Assays Market Segments: Products Forecast - Revenue ($m), 2016-2026
Figure 3.5 Cell-Based Assays Market Segments: Products Forecast - AGR (%), 2016-2026
Figure 3.6 Cell-Based Assay Products Overview, 2016
Figure 3.7 Cell-Based Assays Market Segments: Services Forecast - Revenue ($m), 2016-2026
Figure 3.8 Cell-Based Assays Market Segments: Services Forecast – AGR (%), 2016-2026
Figure 3.9 Cell-Based Assays Market Application Forecasts: Revenue ($m), 2016-2026
Figure 3.10 Drug Discovery Segment Forecast: Revenue ($m), 2016-2026
Figure 3.11 Drug Discovery Segment Forecast: AGR (%), 2016-2026
Figure 3.12 ADME Segment Forecast: Revenue ($m), 2016-2026
Figure 3.13 ADME Segment Forecast: AGR (%), 2016-2026
Figure 3.14 Basic Research Segment Forecast: Revenue ($m), 2016-2026
Figure 3.15 Basic Research Segment Forecast: AGR (%), 2016-2026
Figure 4.1 Cell-Based Assays Market Breakdown by Region: Revenues ($m), Market Shares (%), 2015
Figure 4.2 Cell-Based Assays Market Breakdown by Region: Revenues ($m), Market Shares (%), 2020
Figure 4.3 Cell-Based Assays Market Breakdown by Region: Revenues ($m), Market Shares (%), 2026
Figure 4.4 Global Cell-Based Assays Market, Regional Forecasts: Revenues ($m), 2016-2026
Figure 4.5 US Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Figure 4.6 US Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.7 EU Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Figure 4.8 EU Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.9 EU Market Breakdown by Nation: EU Market Shares (%), 2015
Figure 4.10 EU Market Breakdown by Nation: Revenues ($m), Market Shares (%), 2020
Figure 4.11 EU Market Breakdown by Nation: Revenues ($m), Market Shares (%), 2026
Figure 4.12 EU Market, Top National Forecasts: Revenue ($m), 2016-2026
Figure 4.13 German Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Figure 4.14 German Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.15 French Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Figure 4.16 French Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.17 UK Cell-Based Assays Market Forecast: Revenues ($m), 2016-2026
Figure 4.18 UK Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.19 Spanish Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.20 Spanish Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.21 Italian Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.22 Italian Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.23 Japanese Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.24 Japanese Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.25 BRIC Countries Breakdown by Nation: Market Shares (%), 2015
Figure 4.26 BRIC Countries Breakdown by Nation: Market Shares (%), 2020
Figure 4.27 BRIC Countries Breakdown by Nation: Market Shares (%), 2026
Figure 4.28 BRIC Countries Breakdown by Nation: Revenues ($m), 2016-2026
Figure 4.29 Chinese Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.30 Chinese Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.31 Indian Cell-Based Assays Market Forecast: Revenue ($m), 2016-2026
Figure 4.32 Indian Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.33 Russian Cell-Based Assays Market Forecast: Revenue ($m), 2016-2026
Figure 4.34 Russian Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 4.35 Brazilian Cell-Based Assays Market Forecast: Revenue ($m), 2016-2026
Figure 4.36 Brazilian Cell-Based Assays Market Forecast: AGR (%), 2016-2026
Figure 5.1 ThermoFisher Scientific Historical Sales: Revenue ($m), 2010-2015
Figure 5.2 PerkinElmer Revenue Breakdown: Revenue ($m) for Fiscal Year Ending 3rd January 2016
Figure 5.3 BD Revenue Breakdown: Revenue ($m), 2015
Figure 6.1 Charles River Laboratories Revenue Breakdown: Revenue ($m), 2013-2015
Figure 8.1 Strengths and Weaknesses of the Cell-Based Assay Market, 2016
Figure 8.2 Strengths and Weaknesses of the Cell-Based Assay Market, 2016
Figure 9.1 Projected growth from 2000-2025 with and without a solution for industrialisation of advanced 3D cell-based assays.
Figure 9.2 Proportion of Types of Cell Based Assay Used n 2014 and Predicted in 2024
Figure 10.1 The Cell-Based Assay Submarket Revenue ($m) Breakdown by Products and Services, 2015, 2020 and 2026
Figure 10.2 The Cell-Based Assay Submarket Revenue ($m) Breakdown by Application: Drug Discovery, ADME and Basic Research, 2015, 2020 and 2026
Figure 10.3 Regional Breakdown of the Cell-Based Assay Market by Revenue ($m), 2015, 2020 and 2026